Function Glutathione reductase

glutathione plays key role in maintaining proper function , preventing oxidative stress in human cells. can act scavenger hydroxyl radicals, singlet oxygen, , various electrophiles. reduced glutathione reduces oxidized form of enzyme glutathione peroxidase, in turn reduces hydrogen peroxide (h2o2), dangerously reactive species within cell. in addition, plays key role in metabolism , clearance of xenobiotics, acts cofactor in detoxifying enzymes, participates in transport, , regenerates antioxidants such , vitamins e , c reactive forms. ratio of gssg/gsh present in cell key factor in maintaining oxidative balance of cell, is, critical cell maintains high levels of reduced glutathione , low level of oxidized glutathione disulfide. narrow balance maintained glutathione reductase, catalyzes reduction of gssg gsh.

reduced glutathione reductase, glutathione peroxidase , glutathione interact reduce hydrogen peroxide water, in order protect cell oxidative damage.